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Ns. There was a significant reduction (p = 0.0045) in adherence of S. aureus DisdA to squames when compared to a wild-type strain (Figure 4B). Pre-incubation of S. aureus DisdA with L2v significantly (p = 0.0224) impairedClfB likely binds to loricrin using the ``dock, lock and latch'' mechanismClfB binds to K10 and Fg peptide ligands using the ``dock, lock and latch'' mechanism [28?9]. In order to
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Ctant protein Adeficient mice. Pneumon 2009, 22:143-155. 35. Hyka N, Dayer JM, Modoux C, Kohno T, Edwards CK III, Roux-Lombard P, et al.: Apolipoprotein A-I inhibits the production of interleukin-1beta and tumor necrosis factor-alpha by blocking contact-mediated activation of monocytes by T lymphocytes. Blood 2001, 97:2381-2389. 36. Groves E, Dart AE, Covarelli V, Caron E: Molecular mechanisms of
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Lized challenge to the ability of antibodies to selectively recognize G protein-coupled receptors (GPCR) based on apparent nonspecificity of 49 GPCR antibodies to 19 different GPCRs (the AT1 and AT2 receptors were not among the 19 GPCRs) has called into question the validity of immunological identification of GPCRs [182]. However, Xue et al., [183] using the same antibody as Adams et al., [180] de
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S.orginvestigated. Nasal colonisation was established in specific pathogen-free wild-type FVB (WT) mice and loricrin-deficient mice (Lor2/2) on the same background. To establish colonisation, mice were inoculated intra-nasally with S. aureus Newman Smr (26108 CFU) (hereafter called Newman). Mice were administered streptomycin in their drinking water 24 hours prior to inoculation and for the durati
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In MetaCore Interactome analysis option, networks can be built to see interconnectedness within a data set. Genes in the input list can have physical and functional interactions (such as binding, catalytic, phosphorylation, transcriptional regulation) that are used by the algorithm to build subnetworks ranked by relative enrichment with the uploaded genes and relative saturation of networks with c
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Stories of personal failure in a host of social role experiencesStories of personal failure in a host of social role experiences, experience harmful stigma (from the public, media, mental health professionals, and sometimes significant others), and often develop self-stigma (20). These experiences can erode self-efficacy for coping with their illness or dealing with a broad range of life dem
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Stories of personal failure in a host of social role experiencesStories of personal failure in a host of social role experiences, experience harmful stigma (from the public, media, mental health professionals, and sometimes significant others), and often develop self-stigma (20). These experiences can erode self-efficacy for coping with their illness or dealing with a broad range of life dem
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S DS, et al.: Role of surfactant protein-A (SP-A) in lung injury in response to acute ozone exposure of SP-A deficient mice. Toxicol Appl Pharmacol 2007, 220:72-82. 32. Korfhagen TR, LeVine AM, Whitsett JA: Surfactant protein A (SP-A) gene targeted mice. Biochim Biophys Acta 1998, 1408:296-302. 33. LeVine AM, Hartshorn K, Elliott J, Whitsett J, Korfhagen T: Absence of SP-A modulates innate and ada